File:Three-Dimensional-Architecture-and-Biogenesis-of-Membrane-Structures-Associated-with-Hepatitis-C-ppat.1003056.s007.ogv

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English: Animation through a Z series of 1.996 nm thick digital slices (total thickness ∼140 nm) of a dual-axis tomogram (corresponding to Figure 7), reconstructed from a ∼250 nm thick section of a HCV-infected Huh7.5 cell, fixed 36 hpi. Colored overlay shows a 3D surface model of virus-induced membranes. ER membranes are depicted in dark brown, inner DMV, MMV and DMT membranes in yellowish brown, outer DMV, MMV and MMT membranes in light brown, small vesicles in pink, intermediate filaments in dark blue and the nucleoplasm in violet. Note that most of the DMVs are connected to ER membranes via a neck-like structure.
Date
Source Movie S2 from Romero-Brey I, Merz A, Chiramel A, Lee J, Chlanda P, Haselman U, Santarella-Mellwig R, Habermann A, Hoppe S, Kallis S, Walther P, Antony C, Krijnse-Locker J, Bartenschlager R (2012). "Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication". PLOS Pathogens. DOI:10.1371/journal.ppat.1003056. PMID 23236278. PMC: 3516559.
Author Romero-Brey I, Merz A, Chiramel A, Lee J, Chlanda P, Haselman U, Santarella-Mellwig R, Habermann A, Hoppe S, Kallis S, Walther P, Antony C, Krijnse-Locker J, Bartenschlager R
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December 2012

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